University of ºÚÁÏÊÓÆµ Institutional Biosafety Committee
The University of ºÚÁÏÊÓÆµ Institutional Biosafety Committee (IBC) reviews research with and educational use of biological agents. Its mission is to ensure appropriate biosafety procedures are in place when use of biological agents occurs. The IBC is also established in accordance with the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules ("").
Policy and Procedure
The Office of Environmental and Occupational Health and Safety (EOHS) oversees safety practices with biological agents. The Office of Research Administration (ORA) collaborates with EOHS when that work involves the use of recombinant DNA. Oversight is provided through the Institutional Biosafety Committee.
The following links provide the university policy and procedure for work with biological agents
- Biosafety Guidelines for use of Recombinant DNA (Exempt protocol form)
- Guidelines for teaching laboratories that use BSL2 agents
- IBC Protocol Closure form
- Biological agent incident report form
BIOSAFETY RESOURCES
- The BMBL is a tool for assessing biosafety risk and containment and mitigation practices. It is a best practice manual
- The American Society For Microbiology provides guidelines for biosafety training in teaching labs.
- These guidelines provide a consistent approach to safe work with microorganisms in teaching labs. These guidelines are for work with just BSL-1 and BSL-2 organisms.
- The LBM is a another useful tool for assessing biosafety risk and containment and mitigation practices.
- This list is maintained by the CDC, USDA, and HHS. Work with these agents or toxins requires review by the full IBC. Further, there are export-control restrictions in working with these agents or toxins, in addition to heightened containment practices.
- Some agents or toxins on this list are excluded from theheightened practices, though not from the export-controls, when small quantities are utilized.
- The Federal Select Agent program provides additional guidance on work with these agents and toxins.
- Dual use agents are those that are known to post a significant threat to public health, agricultural crops and plants, animals, the environment, or national security, if used inappropriately. Work with these agents requires full IBC review.
- The Risk Group Database is provided by the American Biological Safety Association. It provides a mechanism to access a summary of risk classifications from the resources listed above and from other resources.
- The LAI is a searchable database describing the various lab acquired infections, which may occur from work with certain biological agents. It may be useful for understanding how to prevent such infections, and ensuring safe biological containment, PPE, and mitigation practices.
- The Ohio EPA regulates the generation, treatment, transportation, and disposal of infectious waste.
- The University of ºÚÁÏÊÓÆµ EOHS department maintains the appropriate permits for generation, treatment, transportation, and disposal of infectious waste.